A new breakthrough in anti-aging research could lead to gene and stem cell therapies that turn back the hands of time.
Scientists are developing treatments in every therapeutic category, from traditional small-molecule drugs to the latest in gene-transfer therapies, as well as exploring immunotherapies, nutritional supplements, genetically modified foods and more.
SIRT1 is a protein that is believed to play important roles in longevity and age-related diseases.
The Cellular Anti-aging Assay (SIRT1 assay) determines the ability of a test material to stimulate SIRT1 protein expression or activity in human cells, which translates to the material’s anti-aging potential.
According to the GenAge database, we now know of >2000 genes that modulate longevity in model organisms, and the drug database lists >400 compounds that can increase longevity in model organisms.
Such approaches are imperative, as is the integration of differing expertise in developing and prioritizing targets, drugs, and therapies for testing.